ResLit - Antimicrobial Resistance Gene & Mutation Database

Protein ChangeA237T

Validation StatusCandidate

Databases

Reslit

Overview

Mechanism: impaired catalytic activity
Resistance To: carbapenems
Organisms: Mycobacterium tuberculosis
Papers: 1

Paper Information1

Can inhibitor-resistant substitutions in the Mycobacterium tuberculosis β-Lactamase BlaC lead to clavulanate resistance?: a biochemical rationale for the use of β-lactam–β-lactamase inhibitor combinations.

PMID 24060876 · 2013

Mutation Information

blaGES-1: p.A237T

Protein Change: A237T
Organisms: Mycobacterium tuberculosis
Confers Resistance To: carbapenems
Effect on Function: impaired catalytic activity
Validation Method: site-directed mutagenesis
Source Database: Reslit

Comments (0)

No comments yet. Be the first to comment!

Mutation Information

Browse AMR Mutations

Mutation Information