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Browse Mutations rpoBD450V

GenerpoB

Protein ChangeD450V

Nucleotide ChangeA1349T

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: rifampicin
Organisms: Mycobacterium tuberculosis
Papers: 1

Paper Information1

1

Signatures of Selection at Drug Resistance Loci in Mycobacterium tuberculosis.

PMID 29404424 · 2018

dominant RIF resistance mutation

Mutation Information

rpoB: p.D450V / c.A1349T

Protein Change: D450V
Nucleotide Change: A1349T
Organisms: Mycobacterium tuberculosis
Confers Resistance To: rifampicin
Validation Method: whole-genome sequencing
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research