ResLit - Antimicrobial Resistance Gene & Mutation Database

GeneblaOXA-61

beta-lactamase

Nucleotide ChangeG57T

Validation StatusCandidate

Databases

Reslit

Overview

Mechanism: inactivates bla OXA-61 gene expression, inhibits transcription resulting in the isolate becoming sensitive to ampicillin
Resistance To: ampicillin, beta lactams
Organisms: Campylobacter jejuni, Campylobacter coli
Papers: 2

Paper Information2

Genomic diversity of Campylobacter jejuni and Campylobacter coli isolates recovered from human and poultry in Australia and New Zealand, 2017 to 2019.

PMID 39499243 · 2024

Mutation Information

blaOXA-61: c.G57T

Nucleotide Change: G57T
Organisms: Campylobacter jejuni, Campylobacter coli
Confers Resistance To: ampicillin
Effect on Function: inactivates bla OXA-61 gene expression
Validation Method: genomic screening
Source Database: Reslit

Molecular characterization of Campylobacter spp. recovered from beef, chicken, lamb and pork products at retail in Australia.

PMID 32730330 · 2020

Inhibits transcription, leading to sensitivity to ampicillin despite presence of the gene.

Mutation Information

blaOXA-61: c.G57T

Nucleotide Change: G57T
Organisms: Campylobacter coli, Campylobacter jejuni
Confers Resistance To: beta lactams
Effect on Function: inhibits transcription resulting in the isolate becoming sensitive to ampicillin
Validation Method: genomic analysis
Source Database: Reslit

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