ResLit - Antimicrobial Resistance Gene & Mutation Database

GeneporA

major outer membrane porin

Protein ChangeG56D

Validation StatusConfirmed2+ DBs

Databases

Reference Gene CatalogResFinder DatabaseReslit

Overview

Mechanism: Efflux, group 2 major outer membrane porin protein PorA
Resistance To: ertapenem, ertapenem|meropenem, carbapenems
Organisms: Campylobacter jejuni
Papers: 1

Paper Information1

Recurrent Campylobacter jejuni Infections with In Vivo Selection of Resistance to Macrolides and Carbapenems: Molecular Characterization of Resistance Determinants.

PMID 37358443 · 2023

insertion of GAC codon in extracellular loop L3

Contributes to increased resistance

porA

Mutation Information

porA: p.G56D

Protein Change: G56D
Organisms: Campylobacter jejuni
Confers Resistance To: ertapenemertapenem|meropenemcarbapenems
Effect on Function: Efflux; group 2 major outer membrane porin protein PorA
Validation Method: genetic analysis
Source Database: ReslitResFinder DatabaseReference Gene Catalog

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