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Browse Mutations ompCA226D

GeneompC

outer membrane porin

Protein ChangeA226D

Validation StatusCandidate

Databases

Reslit

Overview

Mechanism: increased susceptibility to β-lactam antibiotics
Resistance To: ampicillin|piperacillin
Organisms: Escherichia coli
Papers: 1

Paper Information1

1

The A226D Mutation of OmpC Leads to Increased Susceptibility to β-Lactam Antibiotics in Escherichia coli.

PMID 39194538 · 2024

The A226D mutation in OmpC leads to increased susceptibility to β-lactam antibiotics.

Mutation Information

Protein Change: A226D
Organisms: Escherichia coli
Confers Resistance To: ampicillin|piperacillin
Effect on Function: increased susceptibility to β-lactam antibiotics
Validation Method: MIC measurement and survival assays
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research