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Browse Mutations penAL421P

GenepenA

penicillin-binding protein 2 (PBP 2)

Protein ChangeL421P

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: penicillin
Organisms: Neisseria gonorrhoeae
Papers: 1

Paper Information1

1

Molecular Epidemiology, Antimicrobial Surveillance, and PK/PD Analysis to Guide the Treatment of Neisseria gonorrhoeae Infections.

PMID 34683991 · 2021

Mutations in the penA gene contribute to penicillin resistance.

Mutation Information

Protein Change: L421P
Organisms: Neisseria gonorrhoeae
Confers Resistance To: penicillin
Validation Method: whole-genome sequencing
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research