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Browse Mutations rpoBD435T

GenerpoB

Protein ChangeD435T

Validation StatusEstablished

Databases

Card Database

Overview

Mechanism: single resistance variant
Resistance To: rifampicin
Organisms: Mycobacterium tuberculosis
Papers: 1

Paper Information1

1

Characterization of mutations causing rifampicin and isoniazid resistance of Mycobacterium tuberculosis in Syria.

PMID 22708343 · 2012

Mycobacterium tuberculosis rpoB with mutations conferring resistance to rifampicin; CARD accession: CARD:3003283

Mutation Information

Protein Change: D435T
Organisms: Mycobacterium tuberculosis
Confers Resistance To: rifampicin
Effect on Function: single resistance variant
Source Database: Card Database

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research