Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

GenerpoB

Protein ChangeT427S

Validation StatusConfirmed2+ DBs

Databases

Card DatabaseResFinder Database

Overview

Mechanism: single resistance variant
Resistance To: rifampicin
Organisms: Mycobacterium tuberculosis
Papers: 4

Paper Information4

1

Tuberculosis drug resistance mutation database.

PMID 19209951 · 2009

Mutation Information

Protein Change: T427S
Organisms: Mycobacterium tuberculosis
Confers Resistance To: rifampicin
Source Database: ResFinder Database

2

MUBII-TB-DB: a database of mutations associated with antibiotic resistance in Mycobacterium tuberculosis.

PMID 24731071 · 2014

Mutation Information

Protein Change: T427S
Organisms: Mycobacterium tuberculosis
Confers Resistance To: rifampicin
Source Database: ResFinder Database

3

PMID 978-92-4-008241-0

Mycobacterium tuberculosis rpoB with mutations conferring resistance to rifampicin; CARD accession: CARD:3003283

Mutation Information

Protein Change: T427S
Organisms: Mycobacterium tuberculosis
Confers Resistance To: rifampicin
Effect on Function: single resistance variant
Source Database: Card Database

4

Mutations in the rpoB gene of multidrug-resistant Mycobacterium tuberculosis clinical isolates from India.

PMID 11474030 · 2001

Mycobacterium tuberculosis rpoB with mutations conferring resistance to rifampicin; CARD accession: CARD:3003283

Mutation Information

Protein Change: T427S
Organisms: Mycobacterium tuberculosis
Confers Resistance To: rifampicin
Effect on Function: single resistance variant
Source Database: Card Database

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