ResLit - Antimicrobial Resistance Gene & Mutation Database

GenewalK

histidine kinase

Protein ChangeL10F

Validation StatusConfirmed2+ DBs

Databases

Card DatabaseReference Gene Catalog

Overview

Mechanism: single resistance variant, cell wall metabolism sensor histidine kinase WalK
Resistance To: daptomycin
Organisms: Staphylococcus aureus
Papers: 1

Paper Information1

Additional routes to Staphylococcus aureus daptomycin resistance as revealed by comparative genome sequencing, transcriptional profiling, and phenotypic studies.

PMID 23554895 · 2013

Staphylococcus aureus walK with mutation conferring resistance to daptomycin; CARD accession: CARD:3003794

Mutation Information

walK: p.L10F

Protein Change: L10F
Organisms: Staphylococcus aureus
Confers Resistance To: daptomycin
Effect on Function: single resistance variant
Source Database: Card Database

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