ResLit - Antimicrobial Resistance Gene & Mutation Database

Genepbp2b

penicillin-binding protein 2B

Protein ChangeE475G

Validation StatusEstablished

Databases

Card Database

Overview

Mechanism: single resistance variant
Resistance To: amoxicillin
Organisms: Streptococcus pneumoniae
Papers: 1

Paper Information1

Positive selection in penicillin-binding proteins 1a, 2b, and 2x from Streptococcus pneumoniae and its correlation with amoxicillin resistance development.

PMID 18394970 · 2008

Streptococcus pneumoniae PBP2b conferring resistance to amoxicillin; CARD accession: CARD:3003042

Mutation Information

pbp2b: p.E475G

Protein Change: E475G
Organisms: Streptococcus pneumoniae
Confers Resistance To: amoxicillin
Effect on Function: single resistance variant
Source Database: Card Database

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