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Browse Mutations rpoBV1143G

GenerpoB

Protein ChangeV1143G

Validation StatusEstablished

Databases

Reference Gene Catalog

Overview

Mechanism: DNA-directed RNA polymerase subunit beta RpoB
Resistance To: fidaxomicin
Organisms: Clostridioides difficile
Papers: 1

Paper Information1

1

In vivo emergence of a still uncommon resistance to fidaxomicin in the urgent antimicrobial resistance threat Clostridioides difficile.

PMID 37352110 · 2023

rpoB

Mutation Information

Protein Change: V1143G
Organisms: Clostridioides difficile
Confers Resistance To: fidaxomicin
Effect on Function: DNA-directed RNA polymerase subunit beta RpoB
Source Database: Reference Gene Catalog

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research