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Browse Mutations acrBR620C

GeneacrB

Acriflavin resistance protein B

Protein ChangeR620C

Validation StatusEstablished

Databases

Reference Gene Catalog

Overview

Mechanism: multidrug efflux RND transporter permease subunit AcrB
Resistance To: tigecycline
Organisms: Escherichia coli
Papers: 1

Paper Information1

1

Emergence of tigecycline resistance in Escherichia coli co-producing MCR-1 and NDM-5 during tigecycline salvage treatment.

PMID 30519062 · 2018

acrB

Mutation Information

Protein Change: R620C
Organisms: Escherichia coli
Confers Resistance To: tigecycline
Effect on Function: multidrug efflux RND transporter permease subunit AcrB
Source Database: Reference Gene Catalog

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research