ResLit - Antimicrobial Resistance Gene & Mutation Database

GenemgrB

regulator

Protein ChangeM27K

Validation StatusConfirmed2+ DBs

Databases

Reference Gene CatalogReslit

Overview

Mechanism: PhoP/PhoQ regulatory lipoprotein MgrB
Resistance To: colistin
Organisms: Klebsiella pneumoniae
Papers: 2

Paper Information2

Characterization of Carbapenemase-Producing Klebsiella pneumoniae Isolates from Two Romanian Hospitals Co-Presenting Resistance and Heteroresistance to Colistin.

PMID 36139950 · 2022

mutations in mgrB gene lead to colistin resistance

Mutation Information

mgrB: p.M27K

Protein Change: M27K
Confers Resistance To: colistin
Validation Method: experimental validation in this study
Source Database: Reslit

Rapid Detection of Polymyxin Resistance in Enterobacteriaceae.

PMID 27191712 · 2016

mgrB

Mutation Information

mgrB: p.M27K

Protein Change: M27K
Organisms: Klebsiella pneumoniae
Confers Resistance To: colistin
Effect on Function: PhoP/PhoQ regulatory lipoprotein MgrB
Source Database: Reference Gene Catalog

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