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Browse Mutations mtrDR714H

GenemtrD

membrane transporter component of the MtrC-MtrD-MtrE efflux system

Protein ChangeR714H

Validation StatusEstablished

Databases

Reference Gene Catalog

Overview

Mechanism: multidrug efflux RND transporter permease subunit MtrD
Resistance To: azithromycin
Organisms: Neisseria gonorrhoeae
Papers: 1

Paper Information1

1

Efflux Pump Antibiotic Binding Site Mutations Are Associated with Azithromycin Nonsusceptibility in Clinical Neisseria gonorrhoeae Isolates.

PMID 32843551 · 2020

mtrD

Mutation Information

Protein Change: R714H
Organisms: Neisseria gonorrhoeae
Confers Resistance To: azithromycin
Effect on Function: multidrug efflux RND transporter permease subunit MtrD
Source Database: Reference Gene Catalog

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research