ResLit - Antimicrobial Resistance Gene & Mutation Database

GenepenA

penicillin-binding protein 2 (PBP 2)

Protein ChangeD346DD

Validation StatusEstablished

Databases

Reference Gene Catalog

Overview

Mechanism: penicillin-binding protein PBP2 PenA
Resistance To: beta lactams
Organisms: Neisseria gonorrhoeae
Papers: 2

Paper Information2

Molecular and structural analysis of mosaic variants of penicillin-binding protein 2 conferring decreased susceptibility to expanded-spectrum cephalosporins in Neisseria gonorrhoeae: role of epistatic mutations.

PMID 20704258 · 2010

penA

Mutation Information

penA: p.D346DD

Protein Change: D346DD
Organisms: Neisseria gonorrhoeae
Confers Resistance To: beta lactams
Effect on Function: penicillin-binding protein PBP2 PenA
Source Database: Reference Gene Catalog

The Reflotron Total Cholesterol assay in heparinized venous and capillary blood.

PMID 2358795 · 1990

penA

Mutation Information

penA: p.D346DD

Protein Change: D346DD
Organisms: Neisseria gonorrhoeae
Confers Resistance To: beta lactams
Effect on Function: penicillin-binding protein PBP2 PenA
Source Database: Reference Gene Catalog

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