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Browse Mutations rpoBD543N

GenerpoB

Protein ChangeD543N

Validation StatusEstablished

Databases

Reference Gene Catalog

Overview

Mechanism: DNA-directed RNA polymerase subunit beta RpoB
Resistance To: rifampicin
Organisms: Neisseria meningitidis
Papers: 1

Paper Information1

1

Multicenter study for defining the breakpoint for rifampin resistance in Neisseria meningitidis by rpoB sequencing.

PMID 20606072 · 2010

rpoB

Mutation Information

Protein Change: D543N
Organisms: Neisseria meningitidis
Confers Resistance To: rifampicin
Effect on Function: DNA-directed RNA polymerase subunit beta RpoB
Source Database: Reference Gene Catalog

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research