ResLit - Antimicrobial Resistance Gene & Mutation Database

GenemexR

intergenic region near efflux pump regulator

Protein ChangeQ94Ter

Validation StatusEstablished

Databases

Reference Gene Catalog

Overview

Mechanism: effux pump transcriptional repressor MexR
Resistance To: aztreonam avibactam|carbapenems|cephalosporins|phenicols|vaborbactam
Organisms: Pseudomonas aeruginosa
Papers: 1

Paper Information1

Simultaneous and divergent evolution of resistance to cephalosporin/β-lactamase inhibitor combinations and imipenem/relebactam following ceftazidime/avibactam treatment of MDR Pseudomonas aeruginosa infections.

PMID 36918743 · 2023

mexR

Mutation Information

mexR: p.Q94Ter

Protein Change: Q94Ter
Organisms: Pseudomonas aeruginosa
Confers Resistance To: aztreonam avibactam|carbapenems|cephalosporins|phenicols|vaborbactam
Effect on Function: effux pump transcriptional repressor MexR
Source Database: Reference Gene Catalog

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