ResLit - Antimicrobial Resistance Gene & Mutation Database

Protein ChangeS81I

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: ciprofloxacin|levofloxacin|moxifloxacin|gatifloxacin|gemifloxacin|garenoxacin|norfloxacin
Organisms: Streptococcus pneumoniae
Papers: 1

Paper Information1

Novel Ser79Leu and Ser81Ile Substitutions in the Quinolone Resistance-Determining Regions of ParC Topoisomerase IV and GyrA DNA Gyrase Subunits from Recent Fluoroquinolone-Resistant Streptococcus pneumoniae Clinical Isolates.

PMID 15917550 · 2005

Mutation Information

gyrA: p.S81I

Protein Change: S81I
Organisms: Streptococcus pneumoniae
Confers Resistance To: ciprofloxacin|levofloxacin|moxifloxacin|gatifloxacin|gemifloxacin|garenoxacin|norfloxacin
Validation Method: introduction into R6 background and susceptibility testing
Source Database: Reslit

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