ResLit - Antimicrobial Resistance Gene & Mutation Database

GeneparC

Protein ChangeD78A

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: fluoroquinolones, levofloxacin
Organisms: Streptococcus pneumoniae, Streptococcus pyogenes
Papers: 2

Paper Information2

Horizontal transfer of fluoroquinolone resistance genes in Streptococcus pneumoniae

PMID 16189113 · 2003

Mutations in parC are associated with fluoroquinolone resistance.

Mutation Information

parC: p.D78A

Protein Change: D78A
Organisms: Streptococcus pneumoniae
Confers Resistance To: fluoroquinolones
Validation Method: sequencing and MIC testing
Source Database: Reslit

Identification and Characterization of Fluoroquinolone Non-susceptible Streptococcus pyogenes Clones Harboring Tetracycline and Macrolide Resistance in Shanghai, China.

PMID 29628918 · 2018

Mutation Information

parC: p.D78A

Protein Change: D78A
Organisms: Streptococcus pyogenes
Confers Resistance To: levofloxacin
Validation Method: sequencing
Source Database: Reslit

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