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Browse Mutations acrAG1234A

GeneacrA

efflux pump

Nucleotide ChangeG1234A

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: phenicols
Organisms: Escherichia coli
Papers: 1

Paper Information1

1

Decreased thermal niche breadth as a trade-off of antibiotic resistance.

PMID 35422477 · 2022

Mutations in the promoter region of acrA were associated with increased chloramphenicol resistance.

Mutation Information

Nucleotide Change: G1234A
Organisms: Escherichia coli
Confers Resistance To: phenicols
Validation Method: genomic sequencing and competition experiments
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research