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Browse Mutations parCS60N

GeneparC

Protein ChangeS60N

Validation StatusCandidate

Databases

Reslit

Overview

Mechanism: The mutation of S85I affects the binding conformation of ciprofloxacin.
Resistance To: ciprofloxacin
Organisms: Vibrio cholerae
Papers: 1

Paper Information1

1

Novel multiple mutations in the topoisomerase gene of Haitian variant Vibrio cholerae O1.

PMID 24867982 · 2014

Multiple mutations in the parC gene contribute to ciprofloxacin resistance.

Mutation Information

Protein Change: S60N
Organisms: Vibrio cholerae
Confers Resistance To: ciprofloxacin
Effect on Function: The mutation of S85I affects the binding conformation of ciprofloxacin.
Validation Method: sequencing and molecular docking analysis
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
Help
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research