Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Overview
Cloning and characterization of a DNA gyrase A gene from Escherichia coli that confers clinical resistance to 4-quinolones.
The Ser-83-->Trp mutation in the gyrase A protein was solely responsible for high-level bacterial resistance to nalidixic acid and fluoroquinolones.
gyrA
Molecular mechanisms impact on fluoroquinolone resistance among E.coli from enteric carriage monitoring before prostate biopsy and earliest description of qnrB81.
Mutations in the QRDR of gyrA contribute to fluoroquinolone resistance.
Genomic and phenotypic characterization of antimicrobial resistance in clinical Nocardia species isolates.
Mutations in gyrA correlate with ciprofloxacin resistance
Gatifloxacin activity against quinolone-resistant gyrase: allele-specific enhancement of bacteriostatic and bactericidal activities by the C-8-methoxy group.
Comparative genomics of quinolone-resistant Escherichia coli from broilers and humans in Norway.
Contributions of individual mechanisms to fluoroquinolone resistance in 36 Escherichia coli strains isolated from humans and animals.
Quinolone resistance-determining region in the DNA gyrase gyrA gene of Escherichia coli.
gyrA
Mutations in gyrA and parC genes in nalidixic acid-resistant Escherichia coli strains from food products, humans and animals.
4-Quinolone resistance mutations in the DNA gyrase of Escherichia coli clinical isolates identified by using the polymerase chain reaction.
Escherichia coli gyrA conferring resistance to fluoroquinolones; CARD accession: CARD:3003294
Genetic evidence for a role of parC mutations in development of high-level fluoroquinolone resistance in Escherichia coli.
gyrA
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