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Browse Mutations gyrBE793K

GenegyrB

Protein ChangeE793K

Nucleotide ChangeG2379A

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: fluoroquinolones
Organisms: Escherichia coli
Papers: 1

Paper Information1

1

Thiophene antibacterials that allosterically stabilize DNA-cleavage complexes with DNA gyrase.

PMID 28507124 · 2017

Mutations in gyrB confer resistance to fluoroquinolones

Mutation Information

gyrB: p.E793K / c.G2379A

Protein Change: E793K
Nucleotide Change: G2379A
Organisms: Escherichia coli
Confers Resistance To: fluoroquinolones
Validation Method: isolation and identification of E. coli mutants resistant to compound 1 and its analogs with mutations that mapped to this enzyme
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
Help
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research