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Browse Mutations gyrBA372V

GenegyrB

Protein ChangeA372V

Validation StatusConfirmed2+ DBs

Databases

Reference Gene CatalogReslit

Overview

Mechanism: DNA topoisomerase (ATP-hydrolyzing) subunit B GyrB
Resistance To: ciprofloxacin|levofloxacin|ofloxacin, quinolones
Organisms: Pseudomonas aeruginosa
Papers: 1

Paper Information1

1

Mutations in gyrB play an important role in ciprofloxacin-resistant Pseudomonas aeruginosa.

PMID 30804676 · 2019

gyrB

Mutation Information

Protein Change: A372V
Organisms: Pseudomonas aeruginosa
Confers Resistance To: ciprofloxacin|levofloxacin|ofloxacinquinolones
Effect on Function: DNA topoisomerase (ATP-hydrolyzing) subunit B GyrB
Validation Method: sequencing
Source Database: ReslitReference Gene Catalog

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
Help
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research