ResLit - Antimicrobial Resistance Gene & Mutation Database

Protein ChangeV164M

Validation StatusCandidate

Databases

Reslit

Overview

Mechanism: predicted to affect the function of PmrB based on SIFT score (<0.05)
Resistance To: colistin
Organisms: Salmonella enterica, Escherichia coli
Papers: 2

Paper Information2

Genomic Characteristics of Colistin-Resistant Salmonella enterica subsp. enterica Serovar Infantis from Poultry Farms in the Republic of Serbia.

PMID 33321688 · 2020

Mutation Information

pmrB: p.V164M

Protein Change: V164M
Organisms: Salmonella enterica
Confers Resistance To: colistin
Validation Method: WGS and experimental validation
Source Database: Reslit

In vitro reduction of colistin susceptibility and comparative genomics reveals multiple differences between MCR-positive and MCR-negative colistin-resistant Escherichia coli.

PMID 31354315 · 2019

Mutation Information

pmrB: p.V164M

Protein Change: V164M
Organisms: Escherichia coli
Confers Resistance To: colistin
Effect on Function: predicted to affect the function of PmrB based on SIFT score (<0.05)
Validation Method: whole-genome sequencing and PCR
Source Database: Reslit

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