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Browse Mutations rlmIK201A

GenerlmI

Protein ChangeK201A

Validation StatusCandidate

Databases

Reslit

Overview

Mechanism: inhibits RlmI activity
Resistance To: kanamycin
Organisms: Escherichia coli
Papers: 1

Paper Information1

1

c-di-GMP inhibits rRNA methylation and impairs ribosome assembly in the presence of kanamycin.

PMID 39870966 · 2025

mutation in rlmI reduces antibiotic tolerance

Mutation Information

Protein Change: K201A
Organisms: Escherichia coli
Confers Resistance To: kanamycin
Effect on Function: inhibits RlmI activity
Validation Method: streptavidin blotting assays
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
Help
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research