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Browse Mutations mexRA164C

GenemexR

intergenic region near efflux pump regulator

Protein ChangeA164C

Validation StatusCandidate

Databases

Reslit

Overview

Mechanism: inactivating the OprD porin within the cellular membrane
Resistance To: meropenem
Organisms: Pseudomonas aeruginosa
Papers: 1

Paper Information1

1

High level non-carbapenemase carbapenem resistance by overlaying mutations of mexR, oprD, and ftsI in Pseudomonas aeruginosa.

PMID 39555917 · 2025

Mutation Information

Protein Change: A164C
Organisms: Pseudomonas aeruginosa
Confers Resistance To: meropenem
Effect on Function: inactivating the OprD porin within the cellular membrane
Validation Method: mutant construction and complementation
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research