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Browse Mutations datS180F

Genedat

Protein ChangeS180F

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: beta lactams
Papers: 1

Paper Information1

1

A S(180)F substitution in D-alanine aminotransferase confers resistance to β-chloro-D-alanine in Staphylococcus aureus.

PMID 41232672 · 2025

The S180F mutation in Dat reduces enzyme activity and confers resistance to BCDA.

Mutation Information

Protein Change: S180F
Confers Resistance To: beta lactams
Validation Method: mutant analysis and enzyme kinetics
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research