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Browse Mutations parEE486K

GeneparE

Protein ChangeE486K

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: fluoroquinolones
Organisms: Clostridium perfringens
Papers: 1

Paper Information1

1

Comparison of the metabolic activities of four wild-type Clostridium perfringens strains with their gatifloxacin-selected resistant mutants.

PMID 19855959 · 2009

Mutation in topoisomerase IV gene

Mutation Information

Protein Change: E486K
Organisms: Clostridium perfringens
Confers Resistance To: fluoroquinolones
Validation Method: sequencing and MIC testing
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
Help
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research