ResLit - Antimicrobial Resistance Gene & Mutation Database

Protein ChangeP105T

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: fluoroquinolones, ciprofloxacin
Organisms: Pseudomonas aeruginosa
Papers: 2

Paper Information2

Prevalence, resistance mechanisms, and susceptibility of multidrug-resistant bloodstream isolates of Pseudomonas aeruginosa.

PMID 20086165 · 2010

Mutation Information

parC: p.P105T

Protein Change: P105T
Organisms: Pseudomonas aeruginosa
Confers Resistance To: fluoroquinolones
Validation Method: point mutations resulting in amino acid changes were commonly found in the QRDR of gyrA (T83I, D87N, and D87G) and parC (S87L and P105T)
Source Database: Reslit

Characterization of antimicrobial resistance mechanisms in carbapenem-resistant Pseudomonas aeruginosa carrying IMP variants recovered from a Mexican Hospital.

PMID 30288063 · 2018

Mutation Information

parC: p.P105T

Protein Change: P105T
Organisms: Pseudomonas aeruginosa
Confers Resistance To: ciprofloxacin
Source Database: Reslit

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