ResLit - Antimicrobial Resistance Gene & Mutation Database

GenemgrB

regulator

Protein ChangeR248P

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: colistin
Organisms: Klebsiella pneumoniae
Papers: 1

Paper Information1

Prevalence and molecular characteristics of colistin-resistant isolates among carbapenem-resistant Klebsiella pneumoniae in Central South China: a multicenter study.

PMID 39755702 · 2025

Mutations in mgrB and TCS-related genes were identified as mechanisms of colistin resistance.

Mutation Information

mgrB: p.R248P

Protein Change: R248P
Organisms: Klebsiella pneumoniae
Confers Resistance To: colistin
Validation Method: RT-qPCR and PCR-based Sanger sequencing
Source Database: Reslit

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