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ResLit

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Browse Mutations pncAA121D

GenepncA

Protein ChangeA121D

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: pyrazinamide
Organisms: Mycobacterium tuberculosis
Papers: 1

Paper Information1

1

Revisiting the mutant prevention concentration to guide dosing in childhood tuberculosis.

PMID 28333284 · 2017

PncA mutations are associated with pyrazinamide resistance.

Mutation Information

Protein Change: A121D
Organisms: Mycobacterium tuberculosis
Confers Resistance To: pyrazinamide
Validation Method: reported in cited literature
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
Help
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research