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Browse Mutations gyrAI549L

GenegyrA

Protein ChangeI549L

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: delafloxacin|ciprofloxacin|levofloxacin|moxifloxacin
Organisms: Escherichia coli
Papers: 1

Paper Information1

1

Analysis of molecular mechanisms of delafloxacin resistance in Escherichia coli.

PMID 39488602 · 2024

Mutations in QRDRs are associated with delafloxacin resistance

Mutation Information

Protein Change: I549L
Organisms: Escherichia coli
Confers Resistance To: delafloxacin|ciprofloxacin|levofloxacin|moxifloxacin
Validation Method: whole-genome sequencing and MIC testing
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
Help
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research