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Browse Mutations gyrAL416F

GenegyrA

Protein ChangeL416F

Nucleotide ChangeC1247T

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: fluoroquinolones
Organisms: Escherichia coli
Papers: 1

Paper Information1

1

Nalidixic acid-a good marker of fluoroquinolone resistance mechanisms in Escherichia coli.

PMID 40401973 · 2025

Mutation Information

gyrA: p.L416F / c.C1247T

Protein Change: L416F
Nucleotide Change: C1247T
Organisms: Escherichia coli
Confers Resistance To: fluoroquinolones
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
Help
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research