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Browse Mutations katGT315S

GenekatG

Protein ChangeT315S

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: isoniazid
Organisms: Mycobacterium tuberculosis
Papers: 1

Paper Information1

1

Fitness Effect of the Isoniazid Resistance Mutation S315T of the Catalase-Peroxidase Enzyme KatG of Mycobacterium tuberculosis.

PMID 40580943 · 2025

S315T mutation in KatG leads to isoniazid resistance

Mutation Information

Protein Change: T315S
Organisms: Mycobacterium tuberculosis
Confers Resistance To: isoniazid
Validation Method: phylogenetic tree inference and ancestral sequence reconstruction
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
Help
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research