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Browse Mutations gyrBE474K

GenegyrB

Protein ChangeE474K

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: ofloxacin|levofloxacin|gemifloxacin
Organisms: Streptococcus pneumoniae
Papers: 1

Paper Information1

1

Genetic analyses of mutations contributing to fluoroquinolone resistance in clinical isolates of Streptococcus pneumoniae.

PMID 11709333 · 2001

Mutation Information

Protein Change: E474K
Organisms: Streptococcus pneumoniae
Confers Resistance To: ofloxacin|levofloxacin|gemifloxacin
Validation Method: genetic transformation
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
Help
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research