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Browse Mutations parES115P

GeneparE

Protein ChangeS115P

Nucleotide ChangeT343C

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: ciprofloxacin
Organisms: Streptococcus pneumoniae
Papers: 1

Paper Information1

1

Fitness of Streptococcus pneumoniae fluoroquinolone-resistant strains with topoisomerase IV recombinant genes.

PMID 18160515 · 2008

Mutation in parE contributes to fluoroquinolone resistance in Streptococcus pneumoniae.

Mutation Information

parE: p.S115P / c.T343C

Protein Change: S115P
Nucleotide Change: T343C
Organisms: Streptococcus pneumoniae
Confers Resistance To: ciprofloxacin
Validation Method: transformation and MIC testing
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
Help
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research