ResLit - Antimicrobial Resistance Gene & Mutation Database

Protein ChangeY319D

Validation StatusConfirmed2+ DBs

Databases

Card DatabaseReslit

Overview

Mechanism: single resistance variant
Resistance To: ethambutol, rifampicin
Organisms: Mycobacterium tuberculosis
Papers: 2

Paper Information2

Performance assessment of the GenoType MTBDRsl test and DNA sequencing for detection of second-line and ethambutol drug resistance among patients infected with multidrug-resistant Mycobacterium tuberculosis.

PMID 21562102 · 2011

Mutation Information

embB: p.Y319D

Protein Change: Y319D
Organisms: Mycobacterium tuberculosis
Confers Resistance To: ethambutol
Validation Method: GenoType MTBDR sl test and DNA sequencing
Source Database: Reslit

Lack of correlation between embB mutation and ethambutol MIC in Mycobacterium tuberculosis clinical isolates from China.

PMID 17846128 · 2007

Mycobacterium tuberculosis embB with mutation conferring resistance to rifampicin; CARD accession: CARD:3003465

Mutation Information

embB: p.Y319D

Protein Change: Y319D
Organisms: Mycobacterium tuberculosis
Confers Resistance To: rifampicin
Effect on Function: single resistance variant
Source Database: Card Database

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