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Browse Mutations gyrAY524H

GenegyrA

Protein ChangeY524H

Nucleotide ChangeT1570C

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: ciprofloxacin
Organisms: Mycobacterium smegmatis, Mycobacterium tuberculosis
Papers: 1

Paper Information1

1

Induction of mycobacterial resistance to quinolone class antimicrobials.

PMID 22564842 · 2012

Mutation Y524H in gyrA was identified in ciprofloxacin-resistant mutants.

Mutation Information

gyrA: p.Y524H / c.T1570C

Protein Change: Y524H
Nucleotide Change: T1570C
Organisms: Mycobacterium smegmatis, Mycobacterium tuberculosis
Confers Resistance To: ciprofloxacin
Validation Method: nucleotide sequence analysis
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
Help
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research