ResLit - Antimicrobial Resistance Gene & Mutation Database

Protein ChangeC14*

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: pyrazinamide
Organisms: Mycobacterium tuberculosis
Papers: 2

Paper Information2

A Multinational Analysis of Mutations and Heterogeneity in PZase, RpsA, and PanD Associated with Pyrazinamide Resistance in M/XDR Mycobacterium tuberculosis.

PMID 28630430 · 2017

Mutation Information

pncA: p.C14*

Protein Change: C14*
Organisms: Mycobacterium tuberculosis
Confers Resistance To: pyrazinamide
Validation Method: whole-genome sequencing and enzymatic activity testing (Wayne's assay)
Source Database: Reslit

Whole-Genome Sequencing of Drug-Resistant Mycobacterium tuberculosis Strains, Tunisia, 2012-2016.

PMID 30789128 · 2019

Mutation Information

pncA: p.C14*

Protein Change: C14*
Organisms: Mycobacterium tuberculosis
Confers Resistance To: pyrazinamide
Validation Method: whole-genome sequencing
Source Database: Reslit

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