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Browse Mutations lcpAE146K

GenelcpA

Protein ChangeE146K

Validation StatusCandidate

Databases

Reslit

Overview

Mechanism: enhanced susceptibility to β-lactam antibiotics
Resistance To: beta lactams|vancomycin|oxacillin
Organisms: Staphylococcus aureus
Papers: 1

Paper Information1

1

none

mutation in lcpA affects resistance to beta-lactam, vancomycin, and oxacillin

Mutation Information

Protein Change: E146K
Organisms: Staphylococcus aureus
Confers Resistance To: beta lactams|vancomycin|oxacillin
Effect on Function: enhanced susceptibility to β-lactam antibiotics
Validation Method: mutant analysis showed altered resistance profiles
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
Help
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research