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Browse Mutations gyrAH45Q

GenegyrA

Protein ChangeH45Q

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: fluoroquinolones
Papers: 1

Paper Information1

1

Targeting efflux pumps prevents the multi-step evolution of high-level resistance to fluoroquinolone in Pseudomonas aeruginosa.

PMID 39982069 · 2025

Mutation Information

Protein Change: H45Q
Confers Resistance To: fluoroquinolones
Validation Method: whole-genome sequencing and MIC testing
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
Help
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research