ResLit - Antimicrobial Resistance Gene & Mutation Database

Protein ChangeP527T

Validation StatusCandidate

Databases

Reslit

Overview

Paper Information2

The Versatile Mutational Resistome of Pseudomonas aeruginosa.

Specific variants in ftsI reduce carbapenem susceptibility in Pseudomonas aeruginosa.

Mutations in the PB domain of ftsI reduce carbapenem susceptibility while increasing susceptibility to cefiderocol and piperacillin.

Protein Change: P527T
Confers Resistance To: carbapenems
Validation Method: Antimicrobial susceptibility testing and molecular modeling
Source Database: Reslit

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