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Explore antimicrobial resistance mutations from the literature

ResLit

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Browse Mutations pncAL10R

GenepncA

Protein ChangeL10R

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: pyrazinamide
Organisms: Mycobacterium tuberculosis
Papers: 1

Paper Information1

1

Characterization of extensively drug-resistant Mycobacterium tuberculosis isolates circulating in Siberia.

PMID 25186134 · 2014

mutations in pncA are associated with pyrazinamide resistance

Mutation Information

Protein Change: L10R
Organisms: Mycobacterium tuberculosis
Confers Resistance To: pyrazinamide
Validation Method: sequencing and MIC testing
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
Help
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research