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Browse Mutations gyrAS447F

GenegyrA

Protein ChangeS447F

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: fluoroquinolones
Papers: 1

Paper Information1

1

Whole genome sequencing based characterization of extensively drug-resistant Mycobacterium tuberculosis isolates from Pakistan.

PMID 25719196 · 2015

Mutations in the gyrA gene associated with fluoroquinolone resistance

Mutation Information

Protein Change: S447F
Confers Resistance To: fluoroquinolones
Validation Method: whole genome sequencing
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
Help
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research