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Browse Mutations pmrBG188S

GenepmrB

Protein ChangeG188S

Validation StatusCandidate

Databases

Reslit

Overview

Mechanism: alteration of the HAMP domain
Resistance To: colistin
Organisms: Pseudomonas aeruginosa
Papers: 1

Paper Information1

1

Mutations in pmrB Confer Cross-Resistance between the LptD Inhibitor POL7080 and Colistin in Pseudomonas aeruginosa.

PMID 31235628 · 2019

Mutation Information

Protein Change: G188S
Organisms: Pseudomonas aeruginosa
Confers Resistance To: colistin
Effect on Function: alteration of the HAMP domain
Validation Method: MIC assays
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
Help
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research