ResLit - Antimicrobial Resistance Gene & Mutation Database

Protein ChangeL17R

Validation StatusCandidate

Databases

Reslit

Overview

Mechanism: predicted to affect the function of PmrB based on SIFT score (<0.05)
Resistance To: colistin
Organisms: Escherichia coli
Papers: 1

Paper Information1

In vitro reduction of colistin susceptibility and comparative genomics reveals multiple differences between MCR-positive and MCR-negative colistin-resistant Escherichia coli.

PMID 31354315 · 2019

Mutation Information

pmrB: p.L17R

Protein Change: L17R
Organisms: Escherichia coli
Confers Resistance To: colistin
Effect on Function: predicted to affect the function of PmrB based on SIFT score (<0.05)
Validation Method: whole-genome sequencing and PCR
Source Database: Reslit

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