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Browse Mutations pmrBC340F

GenepmrB

Protein ChangeC340F

Validation StatusCandidate

Databases

Reslit

Overview

Mechanism: mutant PmrB leads to cross-resistance to aminoglycosides and colistin
Resistance To: polymyxin b
Organisms: Pseudomonas aeruginosa
Papers: 1

Paper Information1

1

Production of Norspermidine Contributes to Aminoglycoside Resistance in pmrAB Mutants of Pseudomonas aeruginosa.

PMID 31383668 · 2019

mutations in pmrB lead to cross-resistance to aminoglycosides and colistin

Mutation Information

Protein Change: C340F
Organisms: Pseudomonas aeruginosa
Confers Resistance To: polymyxin b
Effect on Function: mutant PmrB leads to cross-resistance to aminoglycosides and colistin
Validation Method: sequencing and susceptibility testing
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
Help
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research