ResLit - Antimicrobial Resistance Gene & Mutation Database

Protein ChangeA618T

Validation StatusCandidate

Databases

Reslit

Overview

Mechanism: resistance
Resistance To: fluoroquinolones, ciprofloxacin|levofloxacin|moxifloxacin, ciprofloxacin|levofloxacin
Organisms: Escherichia coli
Papers: 2

Paper Information2

The Resistome, Mobilome, Virulome and Phylogenomics of Multidrug-Resistant Escherichia coli Clinical Isolates from Pretoria, South Africa.

Mutations in gyrB contribute to fluoroquinolone resistance.

Protein Change: A618T
Confers Resistance To: fluoroquinolonesciprofloxacin|levofloxacin|moxifloxacin
Validation Method: PCR and sequencing
Source Database: Reslit

Fluoroquinolone resistance determinants in carbapenem-resistant Escherichia coli isolated from urine clinical samples in Thailand.

less common mutation

Protein Change: A618T
Organisms: Escherichia coli
Confers Resistance To: ciprofloxacin|levofloxacin
Effect on Function: resistance
Validation Method: whole-genome sequencing and antimicrobial susceptibility testing; sequencing
Source Database: Reslit

Comments (0)

No comments yet. Be the first to comment!

Browse AMR Mutations