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Browse Mutations gdpPE183A

GenegdpP

Protein ChangeE183A

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: nafcillin|oxacillin
Papers: 1

Paper Information1

1

Altered PBP4 and GdpP functions synergistically mediate MRSA-like high-level, broad-spectrum β-lactam resistance in Staphylococcus aureus.

PMID 38530033 · 2024

loss-of-function mutation

Mutation Information

Protein Change: E183A
Confers Resistance To: nafcillin|oxacillin
Validation Method: introduction into NGB-sensitive parental strain
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
Help
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research